Diabetes mellitus has emerged as a major public health epidemic in the 21st century. It is predicted that the worldwide prevalence of diabetes will become double from 171 million cases in 2000 to 366 million in 2030. India ranks the highest with respect to diabetes prevalence. Antidiabetic drugs is the cornerstone of diabetes management. The …
Thyroid hormones play an integral role in our physiology – they regulate metabolism, cardiovascular and bone health, neurological functions, and body growth. Aberrations in thyroid hormone levels impact almost all major body systems. Thus, early diagnosis and management of thyroid disorders is extremely important. Precision medicine is vital to determine specific environmental and genetic factors …
Hyperthyroidism and Precision Medicine: Diagnostic Issues Read More »
The outcomes of breast cancer chemotherapeutic management, including response and incidence of adverse events, differ even in patients with similar subtypes, stages, and grades. This variation can be attributed to factors like patient’s age, diet, alcohol use, smoking, menopausal state, other medications, as well as genetic factors. This article discusses the toxicity and adverse events …
Pharmacogenomic Evaluation of Chemotherapy Toxicity in Breast Cancer Read More »
A 60-year-old man was referred to us for uncontrolled hypercholesterolemiaHypercholesterolemia, or hyperlipidemia refers to high cholesterol levels in the blood. If this condition is not controlled, plaque can accumulate in the blood vessels. This can obstruct blood supply to various parts of the body; if your heart or brain doesn’t get enough blood supply, it …
Patient Story – A 60-year-old with uncontrolled Hypercholesterolemia Read More »
Inaugurated by Hon’ble Minister of Finance, Health, Medical and Family Welfare, Telangana, Sri T Harish Rao Garu, the Wellness Centre offers a multidisciplinary, holistic approach towards = preventive health Previous Next
1 21-Gene Assay Helps Postmenopausal Women with Breast Cancer Skip Chemotherapy A new study found that the 21-Gene Assay can help predict postmenopausal women with breast cancer and one to three positive axillary lymph nodes, who can safely forego chemotherapy. These results were published in the journal New England Journal of Medicine and included 5018 …
Sudden cardiac deaths (SCD) have become so common in youngsters, more so in athletes. Understanding the etiologies for such deaths is a huge challenge for physicians worldwide. SCDs in youngsters usually occurs during maximal, vigorous cardiac performance. In this article we shall try to understand if there are ways to predict these SCDs, if genetic …
Sudden cardiac death in young: Genetics and genomics of arrhythmia risk Read More »
Diabetes is a leading cause of morbidity and mortality world over; also a major contributor to the global economic burden. Did you know that by 2030, around 79 million adults will have type 2 diabetes(T2DM) and the access to insulin could just be possible for half the T2DM population? A lot of research has been …
ApOE Polymorphism and Diabetes- Is there an association? Read More »
Cancer is one of the major leading causes of death worldwide. Many therapies and strategies have been applied and are still being discovered in the treatment of this cruel disease. Among them, one such novel genetic study found an RNA domain-containing endonuclease-based genome engineering technology, called the clustered regularly interspaced short palindromic repeat (CRISPR)-associated protein-9 …
CRISPR/Cas9: A powerful genome editing technique for the treatment of cancer cells Read More »
Cancer is a heterogeneous condition and involves deregulation of various genes. MicroRNAs (miRNA) are a class of gene expression regulators, which often function by targeting multiple genes. Here’s all you need to know about the advances and challenges involved with microRNA therapeutics in cancer. Translating miRNA Biology from Bench to Bedside in Cancer MicroRNAs (miRNAs) …
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