ATGC Jan23

DNA methylation alterations as potential biomarkers in systemic lupus erythematosus diagnosis

A recent study suggests that DNA methylation alterations of genes like IFI44L, FOXP3, and MX1 have the potential to be Systemic Lupus Erythematosus (SLE) biomarkers. The results of this study were published in the journal, Lupus.

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Germline mutations and mismatch repair genes implicated in prostate cancer

A recent study revealed evidence on the genetic basis of prostate cancer (PCa) predisposition and the importance of germline genetic testing for patients with a positive family history of PCa or men with high-risk or metastatic disease. A systemic review was conducted and the results of this study were published in the journal, Prostate Cancer and Prostatic Diseases.

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Heterozygous variants in BRCA1 and BRCA2 and mismatch repair genes cause cancer risk in children

A recent study has shown that heterozygous pathogenic germline variants in BRCA1, BRCA2, and mismatch repair genes attribute to cancer risk with reduced penetrance in children and young adults. The results of this study were published in the Journal of the National Cancer Institute.

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Cancer Research Update – A new variant of genetically modified immune T cell that can attack cancer

A new variant of genetically modified immune T cell (HLA-independent T cell receptors) that can attack cancer was developed at the Memorial Sloan Kettering (MSK) Cancer Center. It was developed by genetically modifying an individual’s immune T cells and decking them up with special receptors that can detect cancer in the body.

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Dr. Dattatreyudu Nori – A Radiant Light for the Dark World of Cancer

Prof. Dr. Dattatreyudu Nori is a world-renowned Indian radiation oncologist. He was the principal investigator for numerous clinical trials sponsored by the National Cancer Institute and has received countless national and international awards including the Distinguished Alumnus Award of the Memorial Sloan-Kettering Cancer Center Alumni Society.

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