EPHX1 polymorphisms associated with risk of pre-eclampsia
A recent study has shown that EPHX1 polymorphisms are associated with the risk of pre-eclampsia. The results of this study were published in the Journal of Maternal-Fetal & Neonatal Medicine.
ATGC – General Roundup
Chemo-prophylactic and antitumor potential of vitamin E in breast cancer
A recent study revealed the antitumor and chemo-prophylactic activity of different isoforms of vitamin E (tocopherols and tocotrienols) in preclinical breast cancer studies. The results of this study were published in the journal, Clinical Nutrition ESPEN.
New gene targets for breast cancer found in populations with diverse ancestry
A recent study has established possible target genes for previously identified single-marker associations with breast cancer as well as novel genes implicated in breast cancer development. The results of this study were published in the Journal of Genome medicine.
Single nucleotide polymorphism is associated with ovarian cancer risk
According to a recent study, it was found that Fok1 rs2228570 (single nucleotide polymorphism) is closely associated with ovarian cancer (OC) risk. The results of the study were published in the journal, Cancer Medicine.
DNA methylation alterations as potential biomarkers in systemic lupus erythematosus diagnosis
A recent study suggests that DNA methylation alterations of genes like IFI44L, FOXP3, and MX1 have the potential to be Systemic Lupus Erythematosus (SLE) biomarkers. The results of this study were published in the journal, Lupus.
CYP2E1 polymorphism is associated with colorectal cancer risk
A recent study revealed that CYP2E1 polymorphism rs2031920 is associated with an increased colorectal cancer (CRC) risk. The results of this study were published in the journal, Scientific Reports.
Germline mutations and mismatch repair genes implicated in prostate cancer
A recent study revealed evidence on the genetic basis of prostate cancer (PCa) predisposition and the importance of germline genetic testing for patients with a positive family history of PCa or men with high-risk or metastatic disease. A systemic review was conducted and the results of this study were published in the journal, Prostate Cancer and Prostatic Diseases.
Heterozygous variants in BRCA1 and BRCA2 and mismatch repair genes cause cancer risk in children
A recent study has shown that heterozygous pathogenic germline variants in BRCA1, BRCA2, and mismatch repair genes attribute to cancer risk with reduced penetrance in children and young adults. The results of this study were published in the Journal of the National Cancer Institute.
