ATCG Post Archives - Page 6 of 7

Update on Chimeric Antigen Receptor (CAR) T-cell Therapy

2 Comments / ATCG Post, All ATGC article, ATGC oct / By admin

Surgery, chemotherapy, and radiation therapy have been the cornerstones of cancer treatment for many years. These continue to be the mainstream treatment methods; however, new categories of treatment have recently helped physicians around the world paint a different picture of cancer treatment for people. Over the past decade, immunotherapy, has become what many call the …

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Understanding the Genetics of Familial Adenomatous Polyposis (FAP)

3 Comments / ATCG Post, All ATGC article, ATGC oct / By admin

Familial Adenomatous Polyposis (FAP) is a rare, inherited condition that affects the gastrointestinal tract. Diagnosis is made when 100 or more adenomatous colonic polyps develop. It is caused by a defect in the gene called the adenomatous polyposis coli (APC) gene. It is mostly inherited directly from a parent, but there is a 25 to …

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Role of Genetics in Psychiatric Disorders

1 Comment / ATCG Post, All ATGC article, ATGC oct / By admin

Understanding how the human mind works has always been intriguing to the medical fraternity. It’s over a decade now that psychiatric genetics has taken a strong foothold in terms of gaining an insight into the heritability aspect of mental disorders. Almost all the major psychiatric disorders have a heritable component to it. Psychiatric disorders tend …

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Guidelines for Genetic Testing for Hereditary Breast Cancer

5 Comments / ATCG Post, All ATGC article, ATGC oct / By admin

Among the various types of cancers, one of the most prevalent ones is breast cancer. Although it can be cured completely if detected in the initial stages, there is still a lot of awareness that is required among the people. Breast cancer may occur due to various causes, but about 5-10% cases are hereditary. There …

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Patient Story

2 Comments / ATCG Post, All ATGC article, ATGC oct / By admin

A BREAST LUMP IS PAINLESS, DOESN’T MEAN IS HARMLESS “I had a breast lump, it didn’t hurt, so I didn’t bother…” Above were the lines of a patient who came to my OPD a few days back with a complaint of pain in her breast. Upon examination we found that she had a big lump …

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GenepoweRx and Onco.com sign collaboration agreement to bring world-class affordable advanced gene sequencing technology for cancer patients to India.

3 Comments / ATCG Post, All ATGC article, ATGC sept / By admin

Advanced genetic sequencing for cancer patients would now become more affordable and easily accessible, with the newly announced collaboration between GenepoweRx, India’s most trusted Genetic Testing company, and Onco.com, India’s leading patient-centric cancer care management platform. These two well-known names in their industries have agreed to work together in carrying out advanced cancer genomics test …

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Customization of postoperative pain medication with Pharmacogenomics reduces pain levels

1 Comment / ATCG Post, All ATGC article, ATGC sept / By admin

A recent randomized study suggests that Pharmacogenomics testing could be used effectively to customize postoperative pain medicine following total joint replacement. The results of this study, which included 107 patients, were published in The Journal of Arthroplasty. Pharmacogenomics testing was performed on the patients for about 16 genetic variants, which would affect the pharmacodynamics and …

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Chemosensitivity assay-a promising tool for guiding therapy in Pancreatic adenocarcinoma

1 Comment / ATCG Post, All ATGC article, ATGC sept / By admin

A recent study published in the Cancer Journal established that chemosensitivity assay profiling is a promising tool which can be used for guiding treatment in advanced pancreatic adenocarcinoma (PDAC) patients. This prospective study aimed to establish chemosensitivity assay as a cutting edge approach to guide treatment in patients with metastatic PDAC. The study included 70 …

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New variants associated with statin-associated muscle symptoms are identified

2 Comments / ATCG Post, All ATGC article, ATGC sept / By admin

A latest study found an intronic variant (rs6667912) located within TMEM9 that was significantly associated with clinical statin-associated muscle symptoms (SAMS). The study was published in the journal – Circulation: Genomic and Precision Medicine. Statin therapies are known to frequently show adverse events like SAMS. This double-blind, randomized, placebo controlled clinical trial was conducted to …

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Pharmacogenomics of methotrexate in patients with Rheumatoid arthritis – Current Knowledge and Challenges

4 Comments / ATCG Post, All ATGC article, ATGC sept / By admin

Genetics play a huge role in determining disease activity and treatment response. In this era of precision medicine, genotyping has become extremely important to identify the safest, effective, and cost-effective treatment. Methotrexate(MTX), a conventional synthetic DMARD, is a potent anti-inflammatory and antiproliferative drug and the gold standard for the treatment of RA. However, around 30-40 …

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