Treatments Focus

Autoimmune Disorders

Your immune system is made up of organs and cells that fight germs, parasites, viruses, and cancer cells. Autoimmune diseases occur when the body’s immune system cannot differentiate between your own cells and foreign cells. This makes the body to attack normal healthy cells. There are more than 80 types of autoimmune disorders and can affect almost every part of your body.

The most common diseases are:

  • Rheumatoid arthritis, a form of arthritis that attacks the joints
  • Psoriasis, a condition in which thick, scaly patches of skin is observed
  • Psoriatic arthritis, a type of arthritis affecting with psoriasis
  • Lupus, a disease that damages areas of the body that include joints, skin and organs
  • Thyroid diseases, including Graves’ disease, where the body makes too much thyroid hormone (hyperthyroidism), and Hashimoto’s thyroiditis, where it doesn’t make enough (hypothyroidism) of the hormone

Causes of autoimmune disorders:

The exact cause of autoimmune disorder is not known. But, there are certain risk factors which can increase the chances of developing a particular disorder, that includes: 



to toxins




Common symptoms of autoimmune disorders:

Common symptoms of autoimmune disorders:
The symptoms of autoimmune disease vary from person to person ranging from severe to mild. Multiple factors, such as heredity, environment, and personal health, are likely to contribute to a person’s symptoms.


Joint pain and swelling

Skin problems

Abdominal pain or digestive issues

Recurring fever

Swollen glands

Diagnosis and treatment:

It is difficult for your doctor to diagnose your disease and it usually takes longer time, as many autoimmune diseases have common symptoms. You can provide detailed list of symptoms and a family history of diseases to your doctor. The disease decides the treatment. In most cases, the goal of treatment is to (slow down) your immune system and reduce disease swelling, redness, and pain. To help you feel better, your doctor may prescribe corticosteroids or other medications.

FAQ's :

What is the role of genetics in autoimmune disorders?

Autoimmune illnesses have a complicated genetic base; numerous genes have a role in disease risk, each with relatively minor impacts on its own. Furthermore, it is now known that various autoimmune illnesses are caused by the same genes.

Which gene causes autoimmune disease?

Many researches looking into the genetics of autoimmunity have discovered a common gene known as TYK2. At least 20 autoimmune diseases have been linked to this gene, including multiple sclerosis, type 1 diabetes, rheumatoid arthritis, lupus, and psoriasis.

Are autoimmune diseases hereditary?

A family history of autoimmune illnesses increases your chances of having one yourself. However, autoimmune illnesses are not always passed down from parent to kid in families who are prone to them.

Is there any genetic test available for autoimmune diseases?

Yes, Genetic testing can detect genetic disorders. Advances in science also avail personalised medicine. Personalised medicine is the use of one’s genetic information to prevent, diagnose or treat a disease.

Does exercise and diet help with autoimmune diseases?

Yes, but your doctor will suggest you what kind of diet and exercises you can do based on your disorder.


  1. Autoimmune disorders. Cleveland clinic. Accessed on 28-03-2022.
  2. Autoimmune diseases. Medline plus. Accessed on 28-03-2022.
  3. Autoimmune diseases. Health and education. Accessed on 28-03-2022.
  4. What Are Common Symptoms of Autoimmune Disease? johns Hopkins Medicine. Accessed on 28-03-2022.
  5. Two common disease-associated TYK2 variants impact exon splicing and TYK2 dosage. PubMed Central. Accessed on 28-03-2022.

Related Articles

Book an Appointment to understand how GenepoweRx can help you in treating

Autoimmune Disorders

Meet The Doctors

Dr Kalyan Uppaluri

Dr Hima Challa

Your genetics … Your Test ... Your Health Success

It’s always the word of mouth that’s the best advice. Here are some of our…

Play Video
Play Video

Our Partners

Professional Partnerships

Government Association

CSIR - Centre for Cellular & Molecular Biology

The Centre for Cellular and Molecular Biology (CCMB) under the Council of Scientific and Industrial Research (CSIR) is a premier research organization in frontier areas of modern biology, and promotes centralized national facilities for new and modern techniques in the interdisciplinary areas of biology and bioinformatics.